Simultaneous determination of atorvastatin and ezetimibe from combined pharmaceutical products by micellar electrokinetic capillary chromatography
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چکیده
*Coresspondence: B. Székely-Szentmiklósi. Department of Pharmaceutical Chemistry. Faculty of Pharmacy. University of Medicine and Pharmacy of Tîrgu Mureş. Gh. Marinescu 38, 540139 Tîrgu Mureş, Romania. E-mail: [email protected], [email protected] Simultaneous determination of atorvastatin and ezetimibe from combined pharmaceutical products by micellar electrokinetic capillary chromatography
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Simultaneous determination of ezetimibe and simvastatin in pharmaceutical preparations by MEKC.
A micellar electrokinetic capillary chromatography method was developed and validated for the simultaneous determination of ezetimibe and simvastatin in pharmaceutical preparations. The influence of buffer concentration, buffer pH, sodium dodecyl sulphate (SDS) concentration, organic modifier, capillary temperature, applied voltage, and injection time was investigated, and the method validation...
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